Yes. I've played both and I've found that I like C&C slightly better because there are a few more options. I've not played a lot of clones so YMMV. Mainly, the one I played was Labyrinth Lord and their retro-clone of Gamma World. It worked fine but I found that the Basic Set was also just as good though the clone had some improvements. Right now I'd say that I would use C&C if I was running a game simply because it would be easier to convert my D20 friends to it.